Endocrine Abstracts

Introduction: Poor metabolic control in type 1 diabetes mellitus (T1DM) is associated with micro and macrovascular complications. The implementation of interstitial glucose monitoring systems has contributed to the improvement of glycemic control in recent years.Objectives: Our main objective was to analyze the results of implementing flash glucose monitoring (FGM) devices after 1 year, and see if it managed to improve glycemic control in our patients.</...

Introduction: Morbid obesity is a highly prevalent disease, with bariatric surgery being a fundamental pillar in its treatment.Objectives: To analyze the results of weight loss at 5 years in patients operated by gastric bypass and sleeve at the Regional University Hospital of Malaga.Methods: This is a retrospective observational study, where 104 patients with morbid obesity who underwent bariatric surgery at the Regional University...

Objective: Analyse the features of first patients treated with PCSK9 inhibitors in a specific Familial dyslipidemia Unit and the effects on lipid profile in first months of treatment.Material and methods: Data from patients with heterozygous familial hypercholesterolemia treated with PCSK9 inhibitors were reviewed. Clinical data, physical examination and analytical data were collected at baseline, one month and 3 months.Results: Da...

Introduction: A high percentage of patients diagnosed with Amyotrophic Lateral Sclerosis (ALS) have malnutrition. The nutritional treatment in ALS is essential, affecting muscle strength, quality of life and survival.Objective: To describe the nutritional characteristics of patients evaluated in a specific nutritional Unit in patients with ALS during 3 years.Material and methods: A descriptive study of all patients diagnosed with A...

Introduction: Vitamin D deficiency is very common in our population.It is not clear which is the most effective vitamin D dosing regimen in patients with deficiency.Objective: To compare two vitamin D supplementation regimen in patients with vitamin D deficiency.Material and methods: This is an interventional study: Patients atended in our clinic during May and June 2017 with 25-Hydroxyvitamin D below 30 ng/ml were consecutively se...

Introduction: Cushing disease (CD) results from excessive exposure to glucocorticoids caused by an adrenocorticotropic hormone–secreting pituitary tumor. Inadequately treated CD is associated with significant morbidity and elevated mortality.Objetive: The study purpose was to describe the long term treatment outcomes for CD patients in our hospital.Methods: Retrospective analysis of the records of 36 patients with Cushing dise...

Introduction: Hydroxymethylglutaric aciduria is a rare metabolic disease that is caused by the deficiency of the enzyme 3-hydroxy-3-methylglutaryl-CoA lyase, which participates in the metabolism of leucine and in the formation of ketone bodies. The symptomatology usually occurs in the first two years of life and consists of nausea, vomiting, diarrhea, hypotoniaanddepressed level of consciousness. Metabolic acidosis occurs during crises as a result of the accumulation of metabo...

Introduction: Recently, PCSK9 inhibitors have been approved in our country for familial hypercholesterolemia and for patients with cardiovascular diseases. They are still scarce data in real life patients effects.Objective: Analyse the features of first patients treated with PCSK9 inhibitors in a specific unit of familial dyslipidemia and the effect on lipid profile and other clinical variables.Material and methods: Data from patie...

Introduction: Hyponatraemia is the most common electrolytic disorder in clinical practice. We designed a protocol, based on the latest consensus statements and adapted to our Hospital, for the use of 3% hypertonic saline solution (HSS) in patients with hyponatraemia.Material and methods: Unicentric observational study of a case series. We collected data from 14 adult patients with severe hyponatraemia (serum sodium [SNa] <125 mmol/l) and mild-moderat...

Aim: To assess a perioperative glucocorticoid protocol in transsphenoidal surgery (TSS)and the performance of early post-TSS 08:00 cortisol measurement to detect/exclude secondary adrenal insufficiency.Methods: We selected patients undergoing TSS.In patients with no cushing disease, we checked cortisol/Synachten presurgery, measured 3° postoperative 0800 a.m. cortisol(after 24 h without corticoids) and cortisol/Synachten 3-6 months post-surgery. We ...